Journal of Clinical Research in Paramedical Sciences

[Expand] Volume 6 (2018)
[Expand] Volume 5 (2016)

Journal of Clinical Research in Paramedical Sciences

Volume 6 ,Number 3 (2018) Articles 1 - 3
Page(s) 1-7
Behrouz Baghaiee , Marefat Siahkouhian , Pouran Karimi و Ana Maria Botelho Teixeira , Saeed Dabagh Nikoo kheslat
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Background: Midlife is associated with the development of various cardiovascular diseases such as coronary artery disease, hypertension, and heart failure. The present study aimed to investigate the effects of midlife on cardiac hypertrophy in sedentary rats and its relationship with body weight and oxidative stress. Methods: : In this experimental study, 10 rats aged 11–14 months and 10 rats aged 4 months were used. After keeping the rats under normal housing condition for 10 days, they were slaughtered, and the dimensions of the heart, the extent of heart tissue fibrosis, and levels of H2O2 were measured. Student’s t-test and linear regression were used for the statistical analysis. Results: The findings of this study showed that midlife with low physical activity increases heart weight (P = 0.001), body weight (P = 0.001), and hydrogen peroxide (H2O2) levels (P = 0.001) resulting in a significantly increased ventricular wall thickness (P = 0.001) and ventricular diameter (P = 0.001). The increase in body weight and H2O2 by middle age was significantly associated with an increased ventricular wall thickness (P = 0.001), ventricular diameter (P = 0.001), and heart weight (P = 0.001). Also, there was a significant positive relationship between body weight gain and H2O2 level (P = 0.001). Conclusion: Midlife with low physical activity is associated with pathological concentric cardiac hypertrophy in rats, and subsequently, with weight gain, increased H2O2, increased heart weight and left ventricular wall thickness, and to some extent, left ventricular internal diameter.
Page(s) 8-13
Saeed Ahmadi Barati , Akram ahmadi barati, Leila Farhady, Faranak Helbi
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Background: Orientation means the personal ability to use the senses to determine one’s location and what relationship he/she has with environmental objects and persons. This ability is important for a blind person, so the purpose of this study was to review the developmental status of spatial orientation of students with visual impairments compared with normal ones. Methods: : Subjects of this descriptive-comparative study were 8–12 year old students selected from public schools of Kermanshah. They included 65 students in a cluster-random way as the healthy group. Thirty children with a visual acuity between 0/05 and 0/4 Diopter as the low vision group and 16 ones with maximum visual acuity of 0/04 diopter as the blind group were included from rehabilitative centers. Their spatial orientation capability was measured by throwing a ball towards a target and counting the dribbling of a basketball for 15 seconds. Analysis of data was performed by SPSS software in descriptive and perceptional statistics (one-way ANOVA and post hoc tests). Results: Statistical results showed that there was no significant difference among the 3 groups in throwing the ball towards the target but there was a difference in the other test. Conclusion There was no significant difference in the test of throwing a ball towards the target indicating corrective and compensatory mechanisms, but in dribbling the ball test there were significant differences among the three groups, and the healthy children compared with the visually impaired ones were in a better condition to show the importance of visual receptors for obtaining information from the surroundings.
Page(s) 14-26
Behrouz Baghaiee , Marefat Siahkouhian , Pouran Karimi , Ana Maria Botelho Teixeira , Saeed Dabagh Nikoo kheslat , Khadije Ebrahimi
Abstract |      

Effect of Exercise Training and Middle-age on Pathological and Physiological Cardiac Hypertrophy:Aging is an inevitable process, which is associated with the development of various diseases such as cardiac hypertrophy. Hypertrophy can occur in both pathological and physiological types. Both types can be divided into eccentric or concentric. If age is associated with inactivity, this can lead to pathological heart hypertrophy. However, exercise is able to control pathological hypertrophy, but it could lead to physiological hypertrophy. In This Paper we consider the effects of middle-age on heart and cardiac hypertrophy types and the effects of exercise. Keywords:Middle-age,exercise, cardiac hypertrophy, Pathologic, Physiologic
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